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Mechthild Tegeder

Mechthild Tegeder

Field of Study: Plant Molecular Physiology
Title: Professor
Degrees: Ph.D., University of Göttingen, Germany
Homepage: Homepage/Lab Web Site Link
Google Scholar:  Google Scholar
Office: 401B Abelson Hall
Phone: 509-335-7545
Fax: 509-335-3184
Mailing Address: School of Biological Sciences
Washington State University
PO Box 644236
Pullman,WA 99164-4236


Professor Tegeder’s research deals with the molecular identification and functional characterization of membrane transport processes controlling the partitioning of nitrogen and carbon photoassimilates (e.g. amino acids, ureides and sucrose) in plants. A major focus is to understand the mechanisms regulating organic nitrogen transfer from the location of production in roots or leaves to developing sink organs including seeds. The discovery of essential transporters provides tools important for biotechnological applications in plants. The ultimate goal is to develop strategies aimed at improving nutrient use efficiency, productivity and nutritional quality of important crop plants. Major breakthroughs on transporter functions have been achieved by using transporter repression or overexpression approaches in the model system Arabidopsis and in legumes (i.e. pea and soybean), and complex molecular, genetic, biochemical, physiological, and cell-biological analyses.

Research areas include:
• Nitrogen acquisition and utilization
• Mechanisms of photoassimilate partitioning
• Plant membrane transport proteins
• Amino acid, ureide and sucrose transporter function
• Role of transporters in root, tuber and seed development
• Source-sink interaction and regulation of metabolite transport in the phloem
• Plant-bacteria symbiosis and fixation of atmospheric nitrogen in legumes
• Nitrogen transport across subcellular membranes
• Relationship between nitrogen and carbon metabolism
• Importance of nitrogen partitioning under environmental stress conditions
• Plant nutrient use efficiency, biomass production, and nutritional quality

Representative Publications:

  • Perchlik M. and Tegeder M. (2018) AAP2 amino acid transporter function in photosynthetic and plant nitrogen use efficiency in Arabidopsis. Plant Physiology 178, 174-188. doi: Recommended by F1000
  • Tegeder M. and Masclaux-Daubresse C. (2018) Source and sink mechanisms of nitrogen transport and use. Tansley Review. New Phytologist 217, 5-53. doi: 10.1111/nph.14876
  • Garneau M.G., Tan Q. and Tegeder M. (2018). Amino acid permease AAP6 is essential for nitrogen export from pea nodules, but does not control nitrogen fixation. Journal of Experimental Botany 69, 5205-5219.
  • Tegeder M. and Hammes U. (2018) The way out and in: phloem loading and unloading of amino acids. Current Opinion in Plant Biology 43, 16–21. doi: 10.1016/j.pbi.2017.12.002
  • Perchlik M. and Tegeder M. (2017) Improving plant nitrogen use efficiency through alteration of amino acid transport processes. Plant Physiology 175, 235-247. doi: 10.1104/pp.17.00608. Recommended by F1000
  • Santiago J.P. and Tegeder M. (2017) Implications of nitrogen phloem loading for carbon metabolism and transport during Arabidopsis development. Journal of Integrated Plant Biology 59, 409–421; doi: 10.1111/jipb.12533.
  • Carter A. and Tegeder M. (2016) Increasing nitrogen fixation and seed yield in soybean requires complex adjustments of nodule nitrogen metabolism and partitioning processes; Current Biology 26, 1–8. Highly recommended by F1000
  • Santiago J.P. and Tegeder M. (2016) Connecting source with sink: the role of Arabidopsis AAP8 in phloem loading of amino acids. Plant Physiology 171, 508-521. Highly Recommended by F1000
  • Zhang L., Garneau M.G. Majumdar R., Grant J. and Tegeder M. (2015) Improvement of pea biomass and seed productivity by simultaneous increase of phloem and embryo loading with amino acids. The Plant Journal 81, 134–146. Recommended by F1000
  • Tegeder M. (2014) Transporters involved in source to sink partitioning of amino acids and ureides: opportunities for crop improvement. Journal of Experimental Botany 65, 1865-1878.